Epigenetics

Weinheimer I., Boonrod K., Moser M., Zwiebel M., Füllgrabe M., Krczal G., Wassenegger M. (2010). Analysis of an autoproteolytic activity of rice yellow mottle virus silencing suppressor P1. Biol. Chem. 391: 271-281.

Dalakouras A., Tzanopoulou M., Tsagris M., Wassenegger M., and Kalantidis K. (2010). Hairpin transcription does not necessarily lead to efficient triggering of the RNAi pathway. Transgenic Res. Published online: June 26, 2010, DOI: 10.1007/s11248-010-9416-3.

Dalakouras A., Moser M., Zwiebel M., Krczal G., Hell R. and Wassenegger M. (2009). A hairpin RNA construct residing in an intron efficiently triggered RNA-directed DNA methylation in tobacco. Plant J., Plant J. 60: 840-851.

Schwind N., Zwiebel M., Itaya A., Ding B., Wang M.-B., Krczal G. and Wassenegger M. (2009). RNAi-mediated resistance to Potato spindle tuber viroid in transgenic tomato expressing a viroid hairpin RNA construct. Mol. Plant Pathol. 10: 459-469.

Prins M., Laimer M., Noris E., Schultz J., Wassenegger M. and Tepfer M. (2008). Strategies for antiviral resistance in transgenic plants. Mol. Plant Pathol. 9: 73-83.

Verhoeven J. Th. J., Jansen C. C. C., Roenhorst J. W., Steyer S., Schwind N. and Wassenegger M. (2008). First Report of Solanum jasminoides Infected by Citrus exocortis viroid in Germany and the Netherlands and Tomato apical stunt viroid in Belgium and Germany. Plant Disease 92: 973.

Shiboleth Y. M., Haronsky E., Leibman D., Arazi T., Wassenegger M., Whitham S. A., Gaba V. and Gal-On A. (2007) The Conserved FRNK Box in HC-Pro, a Plant Viral Suppressor of Gene Silencing, Is Required for Small RNA Binding and Mediates Symptom Development. J. Virol. 81: 13135-13148.

Wassenegger M. and Krczal G. (2006). Nomenclature and functions of RNA-directed RNA polymerases. Trends Plant Sci., 11: 142-151.

Wassenegger M. (2005). The role of the RNAi machinery in heterochromatin formation. Cell 122: 13-16.
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Qi Y., Pélissier T., Hunt E., Wassenegger M. and Ding B. (2004). A direct role of RNA structures in phloem-mediated systemic traffic. Plant Cell 16: 1741-1752.
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Vogt U., Pélissier T., Pütz A., Razvi F., Fischer R. and Wassenegger M. (2004). Viroid-induced RNA silencing of GFP-viroid fusion transgenes does not induce extensive spreading of methylation or transitive silencing. Plant J. 38: 107-118.
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Wassenegger M. (2002). Gene silencing-based disease resistance. Transgenic Res. 11: 639-653.

Wassenegger M. (2002). Gene silencing. Internat. Rev. Cytol. 219: 61-113.

Bonin M., Oberstrass J., Vogt U., Wassenegger M. and Nellen W. (2001). Binding of IRE-BP to its cognate RNA sequence: SFM studies on a universal RNA backbone for the analysis of RNA-protein interaction. Biol. Chem. 382: 1157-1162.

Wassenegger M. (2001). Advantages and disadvantages of using PCR techniques to characterize transgenic plants. Mol. Biotech. 17: 73-82.

Wassenegger M. (2000). RNA-directed DNA methylation. Plant Mol. Biol. 43: 203-220.
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Pélissier T. and Wassenegger M. (2000). A DNA target of 30 bp is sufficient for RNA-directed DNA methylation. RNA 6: 55-65.
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Bailey-Serres J., Rochaix J.-D., Wassenegger M. and Filipowicz W. (1999). Plants, their organelles, viruses and transgenes reveal mechanisms and relevance of post-transcriptional processes. EMBO J. 18: 5153-5158.
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Pélissier T., Thalmeir S., Kempe D., Sänger H. L. and Wassenegger M. (1999). Heavy de novo methylation at symmetrical and non-symmetrical sites is a hallmark of RNA-directed DNA methylation. Nucl. Acids Res. 27: 1625-1634.
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Wassenegger M. and Pélissier T. (1999). Signalling in gene silencing. Trends Plant Sci. 4: 207-209.

Schiebel W., Pélissier T., Riedel L., Thalmeir S., Schiebel R., Kempe D., Lottspeich F., Sänger H. L. and Wassenegger M. (1998). Isolation of a RNA-directed RNA polymerase-specific cDNA clone from tomato leaf-tissue mRNA. Plant Cell 10: 2087-2101.
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Wassenegger M. and Pélissier T. (1998). A model for RNA-mediated gene silencing in higher plants. Plant Mol. Biol. 37: 349-362.

Wassenegger M., Spieker R., Riedel L., Thalmeir S., Gast F.-U. and Sänger H. L. (1996). A single nucleotide substitution converts potato spindle tuber viroid (PSTVd) from a noninfectious to an infectious RNA for Nicotiana tabacum. Virology 226: 191-197.
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Riedel L., Volger U., Luckinger R., Pütz A., Sänger H. L. and Wassenegger M. (1996). Molecular analysis of the gene family of the signal recognition particle (SRP) RNA of tomato. Plant Mol. Biol. 31: 113-125.

Riedel L., Pütz A., Hauser M.-T., Luckinger R., Wassenegger M. and Sänger H. L. (1995). Characterization of the SRP RNA population of tomato. Plant Mol. Biol. 27: 669-680.

Wassenegger M., Heimes S. and Sänger H. L. (1994). An infectious viroid RNA replicon evolved from an in vitro-generated noninfectious viroid deletion mutant via a complementary deletion in vivo. EMBO J. 13: 6172-6177.
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Wassenegger M., Heimes S., Riedel L. and Sänger H. L. (1994). RNA-directed de novo methylation of genomic sequences in plants. Cell 76: 567-576.

Book chapters

Müller A. and Wassenegger M. (2004). Control and silencing of transgene expression. In Handbook of Plant Biotechnology 2, Christou, P. and Klee, H. eds. (Wiley), pp 291-330.

Wassenegger M. (1998). Application of PCR to transgenic plants. PCR in Bioanalysis. In Methods in Mol. Biol., 92, S.J. Meltzer (Humana Press Inc., Totowa), pp. 153-164.

Sänger H. L., Schiebel W., Riedel L., Pélissier T. and Wassenegger M. (1996). The possible links between RNA-directed DNA methylation (RdDM), sense and antisense RNA, gene silencing, symptom-induction upon microbial infections and RNA-directed RNA polymerase (RdRP). In Biology of Plant-Microbe Interactions, G. Stacey, B. Mullin, and P.M. Gresshoff, eds. (St. Paul, MN: American Phytopathological Society), pp. 533-540.

Patents

US-Patent (No.: 6,218,142B1): Nucleic acid molecules encoding polypeptides having the enzymatic activity of an RNA-directed RNA polymerase (RdRP). Date of patent: Apr. 17, 2001.


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